7 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsSat, Apr 4th 2026
ReturnsSat, Apr 11th 2026
Nights7
Departing PortJacksonville
Ports of CallJacksonville, Amelia Island, Jekyll Island, St. Simons Island, Savannah, Hilton Head Island, Beaufort, Charleston
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise … 
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7 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Eagle
DepartsMon, Apr 6th 2026
ReturnsMon, Apr 13th 2026
Nights7
Departing PortJacksonville
Ports of CallJacksonville, Amelia Island, Jekyll Island, St. Simons Island, Savannah, Hilton Head Island, Beaufort, Charleston
At a capacity of just 109 guests, American Eagle offers the best qualities of expedition adventure cruising with the refinement, luxury, stability, and land proximity of river cruising. The design of the ship allows rare access into small ports and abilit…
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14 Night Canada - New England Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Patriot
DepartsMon, Apr 6th 2026
ReturnsMon, Apr 20th 2026
Nights14
Departing PortSt. Petersburg
Ports of CallSt. Petersburg, Punta Gorda, Marco Island, Key West (2 Days), Key Biscayne, West Palm Beach, Port Canaveral, Saint Augustine, Sailing Tolomato River, Amelia Island, Jacksonville (2 Days)
American Patriot offers an intimate and luxurious cruising experience, catering to just 125 guests with a focus on comfort, elegance, and coastal exploration. The interior design of the ship features a serene color palette, creating a tranquil ambian…
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7 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsSat, Apr 11th 2026
ReturnsSat, Apr 18th 2026
Nights7
Departing PortCharleston
Ports of CallCharleston, Beaufort, Hilton Head Island, Savannah, St. Simons Island, Jekyll Island, Amelia Island, Jacksonville
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise …
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14 Night U.S. Rivers Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Pioneer
DepartsSat, Apr 11th 2026
ReturnsSat, Apr 25th 2026
Nights14
Departing PortJacksonville
Ports of CallJacksonville, Amelia Island, Sailing Tolomato River, Saint Augustine, Port Canaveral, West Palm Beach, Key Biscayne, Key West (2 Days), Marco Island, Punta Gorda, St. Petersburg (2 Days)
Experience our brand new American Pioneer, tailored for intimate cruising along the Florida Coast, accommodating just 125 guests. Immerse yourself in comfort and elegance as you traverse the serene waters. Delight in spacious staterooms adorned …
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7 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Eagle
DepartsMon, Apr 13th 2026
ReturnsMon, Apr 20th 2026
Nights7
Departing PortCharleston
Ports of CallCharleston, Beaufort, Hilton Head Island, Savannah, St. Simons Island, Jekyll Island, Amelia Island, Jacksonville
At a capacity of just 109 guests, American Eagle offers the best qualities of expedition adventure cruising with the refinement, luxury, stability, and land proximity of river cruising. The design of the ship allows rare access into small ports and abilit…
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14 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipIndependence
DepartsSat, Apr 18th 2026
ReturnsSat, May 2nd 2026
Nights14
Departing PortJacksonville
Ports of CallJacksonville, Fernandina Beach, Jekyll Island, St. Simons Island, Savannah, Hilton Head Island, Beaufort, Charleston, East Coast Inland Passage, Wilmington, Beaufort, Kitty Hawk, Norfolk, St. Michaels, Baltimore
The Independence is equipped with the largest staterooms in the industry with most suites featuring private balconies. With the latest in navigation and safety technology, the Independence is fully stabilized, allowing American Cruise …
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14 Night Canada - New England Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Glory
DepartsSat, Apr 18th 2026
ReturnsSat, May 2nd 2026
Nights14
Departing PortJacksonville
Ports of CallJacksonville, Fernandina Beach, Jekyll Island, St. Simons Island, Savannah, Hilton Head Island, Beaufort, Charleston, East Coast Inland Passage, Wilmington, Beaufort, Kitty Hawk, Norfolk, St. Michaels, Washington, D.C.
American Glory blends the best qualities of expedition adventure cruising with the refinement, luxury, stability, and land proximity of river cruising. Observation and sitting areas will be available at the bow, while a unique Swim/Activity Platform at th…
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7 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Eagle
DepartsMon, Apr 20th 2026
ReturnsMon, Apr 27th 2026
Nights7
Departing PortJacksonville
Ports of CallJacksonville, Amelia Island, Jekyll Island, St. Simons Island, Savannah, Hilton Head Island, Beaufort, Charleston
At a capacity of just 109 guests, American Eagle offers the best qualities of expedition adventure cruising with the refinement, luxury, stability, and land proximity of river cruising. The design of the ship allows rare access into small ports and abilit…
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Ocean View
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14 Night Canada - New England Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Pioneer
DepartsSat, Apr 25th 2026
ReturnsSat, May 9th 2026
Nights14
Departing PortSt. Petersburg
Ports of CallSt. Petersburg, Punta Gorda, Marco Island, Key West (2 Days), Key Biscayne, West Palm Beach, Port Canaveral, Saint Augustine, Sailing Tolomato River, Amelia Island, Jacksonville (2 Days)
Experience our brand new American Pioneer, tailored for intimate cruising along the Florida Coast, accommodating just 125 guests. Immerse yourself in comfort and elegance as you traverse the serene waters. Delight in spacious staterooms adorned …
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Ocean View
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Balcony
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Suite
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7 Night U.S. East Coast Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Eagle
DepartsMon, Apr 27th 2026
ReturnsMon, May 4th 2026
Nights7
Departing PortCharleston
Ports of CallCharleston, Beaufort, Hilton Head Island, Savannah, St. Simons Island, Jekyll Island, Amelia Island, Jacksonville
At a capacity of just 109 guests, American Eagle offers the best qualities of expedition adventure cruising with the refinement, luxury, stability, and land proximity of river cruising. The design of the ship allows rare access into small ports and abilit…
Inside Cabin
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Ocean View
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Balcony
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Suite
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14 Night Canada - New England Cruise
Cruise LineAmerican Cruise Lines
ShipAmerican Patriot
DepartsMon, Apr 27th 2026
ReturnsMon, May 11th 2026
Nights14
Departing PortSt. Petersburg
Ports of CallSt. Petersburg, Punta Gorda, Marco Island, Key West (2 Days), Key Biscayne, West Palm Beach, Port Canaveral, Saint Augustine, Sailing Tolomato River, Amelia Island, Jacksonville (2 Days)
American Patriot offers an intimate and luxurious cruising experience, catering to just 125 guests with a focus on comfort, elegance, and coastal exploration. The interior design of the ship features a serene color palette, creating a tranquil ambian…
Inside Cabin
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Ocean View
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Balcony
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Suite
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Prices are per person, double occupancy, cruise only and on select sailings. Prices shown are for stateroom categories as noted and are shown in US Dollars. Pricing listed includes taxes and fees. Airfare is not included. Prices and itineraries are based on availability and are subject to change without notice.
